Here, we report the novel use of Laser Speckle Rheology (LSR) for measuring anticoagulation and haemodilution status in whole blood ▷. Pengaruh variasi

international normalized ratio (INR) using a Laser Speckle Rheology L. F., Weisel, J. W., Lorand, L. Structural origins of fibrin clot rheology.

Laser Speckle Rheology (LSR) offers a novel, non-contact optical approach for evaluating the frequency-dependent viscoelastic properties of hydrogels. In LSR, a coherent laser beam illuminates the Laser speckle rheology (LSR) offers a new noncontact optical approach. LSR uses an inexpensive laser—similar to a common laser pointer to shine laser light on tissue—plus a camera to image speckle patterns reflected from light-scattering particles in the sample. Abstract We introduce a novel technology, termed laser speckle micro-rheology (LSM) that offers the unique capability to map the viscoelastic properties of the tissue microenvironment. This innovation will provide important insight into mechano-biology of disease progression. © 2020 The Author (s) We have developed and investigated a novel optical approach, Laser Speckle Rheology (LSR), to evaluate a patient’s coagulation status by measuring the viscoelastic properties of blood during coagulation.

Abstract: Laser speckle microrheology is Here, we report a new omni-directional viewing Laser Speckle Rheology (LSR) catheter for mapping the mechanical properties of luminal organs without the Clinical evaluation of whole blood prothrombin time (PT) and international normalized ratio (INR) using a Laser Speckle Rheology sensor. 18 Mar 2019 The optical profiler is based on the principles of Laser Speckle Rheology that quantifies tissue viscoelasticity from light scattering patterns 1 May 2020 Laser Speckle Rheology: Technology Platform. LSR is an optical technique that evaluates the viscoelastic properties of biological tissues and 4 May 2018 Here, we use Laser Speckle Strain Imaging (LSSI) to create highly Laser speckle rheology for evaluating the viscoelastic properties of 6 Jul 2018 Laser Speckle Imaging (LSI) is a full-field characterization technique that can Figure 5.12 Rheology of the polymers D-0.9 (self-healing, pink 11 Nov 2019 In this study, we combined laser speckle imaging with a microfluidic system Assessing blood coagulation status with laser speckle rheology. 12 Jul 2018 Laser Speckle Rheology technology to evaluate the rheological properties of biomaterials. To. 7 test the system, two kind of test samples were 16 Mar 2012 Laser Speckle Rheology (LSR) is a novel optical technology that provides the invaluable potential for mechanical assessment of tissue in situ.

measurement and illumination with a femtosecond laser of variable spectral speckle rheology measurements, Opt. Exp. 22 (2014) 6349- 6361.

av S Larsson · 2019 · Citerat av 2 — Yanai (1973). Laser speckle methods has their origin in solid mechanics and their first On the rheology of dilative granular media: Bridging solid- and fluid-like

Patent number: 10359361. Abstract: Laser speckle microrheology is Here, we report a new omni-directional viewing Laser Speckle Rheology (LSR) catheter for mapping the mechanical properties of luminal organs without the Clinical evaluation of whole blood prothrombin time (PT) and international normalized ratio (INR) using a Laser Speckle Rheology sensor. 18 Mar 2019 The optical profiler is based on the principles of Laser Speckle Rheology that quantifies tissue viscoelasticity from light scattering patterns 1 May 2020 Laser Speckle Rheology: Technology Platform. LSR is an optical technique that evaluates the viscoelastic properties of biological tissues and 4 May 2018 Here, we use Laser Speckle Strain Imaging (LSSI) to create highly Laser speckle rheology for evaluating the viscoelastic properties of 6 Jul 2018 Laser Speckle Imaging (LSI) is a full-field characterization technique that can Figure 5.12 Rheology of the polymers D-0.9 (self-healing, pink 11 Nov 2019 In this study, we combined laser speckle imaging with a microfluidic system Assessing blood coagulation status with laser speckle rheology.

research and clinical medicine. We specifically focus on laser speckle rheology (LSR), a tech-nology that quantifies the mechanical properties of tissues in a rapid, noncontact manner. Approach: In LSR, the shear viscoelastic modulus is measured from the time-variant speckle intensity fluctuations reflected off the tissue.

Within a height of less than 1mm, electroactive polymers are used to generate an oscillating motion (e.g. 400µm travel at 300Hz). Assessing blood coagulation status with laser speckle rheology. MM Tripathi, Z Hajjarian, EM Van Cott, SK Nadkarni. Biomedical optics express 5 (3), 817-831, 14 May 2019 temporal resolution for images of blood flow was achieved with laser speckle contrast imaging (LSCI)9–12 by measuring the spatial speckle 7 Sep 2018 Although rheology provides a method to access the product viscosity, it lacks non -contact full-field monitoring. We apply a simple correlation. Keywords: Speckle, Correlation spectroscopy, Dynamical properties, Optical properties.

Laser Speckle Rheology (LSR) offers a novel, non-contact optical approach for evaluating the frequency-dependent viscoelastic properties of hydrogels. In LSR, a coherent laser beam illuminates the specimen and a high-speed camera acquires the time-varying speckle images. We introduce a novel technology, termed laser speckle micro-rheology (LSM) that offers the unique capability to map the viscoelastic properties of the tissue microenvironment. This innovation will provide important insight into mechano-biology of disease progression. 2016-12-08 · Laser speckle rheology (LSR) is a new optical approach that can quantify the mechanical properties of materials in a non-contact manner by analyzing the temporal fluctuations of laser speckle intensities [7–16].
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Laser speckle rheology (LSR) offers a new, noncontact optical approach. LSR uses an inexpensive laser similar to a common laser pointer to shine laser light on The intravascular laser speckle rheology (ILSR), OCE, and PS-OCT technologies outlined here elegantly lend themselves for integration with other intracoronary technologies such as OCT and IVUS that could place direct mechanical findings within a morphologic context for a composite evaluation of coronary plaque stability to predict the propensity of plaque rupture. (rheology), sets itself of investigate the rheological behaviour and the properties of liquid .

We specifically focus on laser speckle rheology (LSR), a tech-nology that quantifies the mechanical properties of tissues in a rapid, noncontact manner. Approach: In LSR, the shear viscoelastic modulus is measured from the time-variant speckle intensity fluctuations reflected off the tissue.
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Laser Speckle Rheology (LSR) offers a novel, non-contact optical approach for evaluating the frequency-dependent viscoelastic properties of hydrogels. In LSR, a coherent laser beam illuminates the specimen and a high-speed camera acquires the time-varying speckle images.

In LSR, a blood sample is illuminated with laser light and temporal speckle intensity fluctuations are measured using a high-speed CMOS camera. Laser speckle microrheology is used to determine a mechanical property of a biological tissue, namely, an elastic modulus. Speckle frames may be acquired by illuminating a coherent light and capturing back-scattered rays in parallel and cross-polarized states with respect to illumination.

Abstract We introduce a novel technology, termed laser speckle micro-rheology (LSM) that offers the unique capability to map the viscoelastic properties of the tissue microenvironment. This innovation will provide important insight into mechano-biology of disease progression. © 2020 The Author (s)

In LSR, a coherent laser beam illuminates the tissue and temporal speckle intensity fluctuations are analyzed to evaluate mechanical properties. Laser speckle rheology (LSR) is a new technique we have developed to measure the mechanical properties of tissue. By illuminating the sample with coherent laser light and calculating the speckle intensity modulations from reflected laser speckle patterns, LSR calculates τ, the decay time constant of intensity decorrelation which is closely associated with tissue mechanical properties. Evaluation and Correction for Optical Scattering Variations in Laser Speckle Rheology of Biological Fluids Zeinab Hajjarian, Seemantini K. Nadkarni* Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America Abstract Biological fluids fulfill key functionalities such as hydrating, protecting, and nourishing cells Laser speckle rheology (LSR) has been demonstrated to provide important information on tissue mechanical properties by analyzing the time scale of temporal speckle intensity fluctuations, which serves as an index of tissue viscoelasticity. Laser speckle flowmetry can measure CBF changes two-dimensionally in real-time over a large area of cortex. Its spatial resolution is determined by the laser wavelength, the quality of the optics, the optical properties of the tissue, and the amount of pixel averaging to estimate the speckle contrast. Assessing blood coagulation status with laser speckle rheology By Markandey M. Tripathi, Zeinab Hajjarian, Elizabeth M. Van Cott and Seemantini K. Nadkarni Cite Hajjarian, Z. & Nadkarni, S. Compensation for causes of temporal fluctuations of backscattered speckle patterns in laser speckle rheology of biological fluids.

This innovation will provide important insight into mechano-biology of disease progression.